About daptomyci n + vial
Cyclic lipopeptide antibiotic
Used for
- Treats complicated skin and soft-tissue infections caused by susceptible bacteria.
- Treats Staphylococcus aureus bloodstream infections, including right-sided endocarditis.
Usual adult dose
Skin infections: 4 mg/kg intravenously every 24 hours. Bloodstream infections: 6 mg/kg every 24 hours; kidney impairment may require adjustment.
Usual dose in children
Children 1–17 years: 5–10 mg/kg intravenously every 24 hours, depending on infection and age.
Common side effects
- Muscle pain or weakness
- Nausea or diarrhea
- Injection-site reactions
- Increased creatine kinase
Important warnings
- Monitor muscle symptoms and creatine kinase; kidney impairment may increase muscle-injury risk.
- Not indicated for pneumonia; lung surfactant inactivates daptomycin.
- Seek urgent care for breathing difficulty, facial swelling, or severe rash.
- Use only for bacterial infections; susceptibility and treatment duration matter.
Pregnancy
Human pregnancy data are limited; use when a clinician determines expected benefits outweigh potential risks.
Breastfeeding
It is unknown whether daptomycin enters human milk; clinical advice is needed during treatment.
Interactions
- Statins may increase muscle-injury risk; monitoring or temporary interruption may be considered.
- Probenecid can increase daptomycin exposure.
- Warfarin: closer monitoring of blood clotting may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.