About cyclosporin
Calcineurin inhibitor immunosuppressant
Used for
- Prevention of organ transplant rejection
- Treatment of severe rheumatoid arthritis
- Treatment of severe psoriasis
Usual adult dose
Varies by condition and formulation; transplant dosing is weight-based and adjusted to blood levels.
Usual dose in children
Used for organ transplant rejection prevention; dose is weight-based and adjusted to blood levels.
Common side effects
- High blood pressure
- Kidney problems
- Tremor or headache
- Increased risk of infections
Important warnings
- Requires regular blood tests and monitoring of kidney function and blood pressure.
- Do not switch formulations or brands without prescriber supervision.
- Avoid grapefruit and grapefruit juice.
- Increases risk of serious infections and some cancers.
Pregnancy
May be used when necessary, but requires specialist assessment and monitoring.
Breastfeeding
May enter breast milk; use requires an individualized specialist decision.
Interactions
- Many medicines affect cyclosporin levels; examples include certain antibiotics and antifungals.
- Can increase kidney injury risk with other kidney-toxic medicines.
- Avoid grapefruit products.
- St John’s wort can lower cyclosporin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.