About cyclophosphamide
Alkylating chemotherapy and immunosuppressant
Used for
- Treats various cancers, including lymphomas, leukemias, and breast cancer.
- Used for some severe autoimmune diseases, such as lupus nephritis.
Usual adult dose
Dose varies greatly by cancer or condition, treatment schedule, and body surface area; given intravenously under specialist supervision.
Usual dose in children
Used for some childhood cancers; specialist dosing varies by diagnosis, body surface area, and treatment schedule.
Common side effects
- Low blood counts and increased infection risk
- Nausea, vomiting, and loss of appetite
- Hair loss
- Bladder irritation or bleeding
Important warnings
- Can cause severe infection, bleeding, infertility, or secondary cancers.
- Blood counts, kidney function, and urine require monitoring during treatment.
- Adequate hydration and prescribed bladder-protective medicines may reduce bladder injury.
- Seek urgent care for fever, unusual bleeding, or blood in urine.
Pregnancy
Can harm an unborn baby. Avoid during pregnancy unless a specialist determines treatment is essential.
Breastfeeding
Breastfeeding is not recommended during treatment because the medicine can harm the infant.
Interactions
- Other medicines that suppress immunity or damage bone marrow can increase toxicity.
- Live vaccines may cause infection; vaccination plans need specialist review.
- Some medicines can alter cyclophosphamide levels or increase its side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.