About cyclobenzaprine hydrochloride
Centrally acting skeletal muscle relaxant
Used for
- Short-term relief of muscle spasms associated with painful musculoskeletal conditions
Usual adult dose
Usually 5 mg three times daily; may increase to 10 mg three times daily. Use for no more than 2–3 weeks.
Usual dose in children
Not recommended for children under 15 years; use in older adolescents requires clinician guidance.
Common side effects
- Drowsiness
- Dry mouth
- Dizziness
- Constipation
Important warnings
- Can impair driving and coordination; avoid alcohol.
- Avoid with recent heart attack, heart rhythm disorders, or hyperthyroidism.
- Do not use with MAO inhibitors or within 14 days of stopping them.
- Use cautiously in older adults and people with liver problems.
Pregnancy
Human pregnancy information is limited; use only when a clinician determines it is needed.
Breastfeeding
Information is limited; discuss use with a healthcare professional, especially when nursing a newborn.
Interactions
- MAO inhibitors: risk of serious reactions.
- Serotonergic medicines, including some antidepressants and tramadol: risk of serotonin syndrome.
- Alcohol, opioids, and sedatives: increased drowsiness and impaired coordination.
- Medicines with anticholinergic effects: increased dry mouth, constipation, and urinary problems.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.