About cortisone acetate
Oral corticosteroid (glucocorticoid)
Used for
- Hormone replacement for adrenal insufficiency
- Treatment of inflammatory and allergic conditions
Usual adult dose
Adrenal insufficiency: commonly 25–37.5 mg daily in divided doses; other conditions vary.
Usual dose in children
Adrenal insufficiency: commonly 0.5–0.75 mg/kg daily in divided doses; specialist-guided.
Common side effects
- Upset stomach
- Increased appetite and weight gain
- Mood or sleep changes
- Raised blood sugar and blood pressure
Important warnings
- Do not stop long-term treatment suddenly; doses may need gradual reduction.
- Long-term use can weaken bones, suppress immunity, and affect growth in children.
- Infection symptoms may be masked; seek prompt assessment for serious infection.
- Dose may need adjustment during illness, surgery, or injury.
Pregnancy
May be used when needed; the prescriber weighs benefits and risks. Long-term use may affect fetal growth.
Breastfeeding
Usually compatible at replacement doses; larger or prolonged doses may affect milk supply or infant adrenal function.
Interactions
- NSAIDs, such as ibuprofen, may increase stomach-ulcer risk.
- Live vaccines may cause serious infection during immunosuppressive treatment.
- Rifampin, some seizure medicines, and some antifungals can alter cortisone effects.
- Warfarin effects may change; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.