About conjugated estrogen
Conjugated estrogen hormone therapy
Used for
- Relieves menopausal hot flashes and vaginal symptoms
- Prevents osteoporosis after menopause in selected patients
- Treats low estrogen due to ovarian failure or removal
- Used with a progestogen when the uterus is present
Usual adult dose
Usually 0.3–0.625 mg by mouth once daily for menopausal symptoms; dose depends on indication.
Common side effects
- Breast tenderness
- Headache
- Nausea
- Vaginal spotting or bleeding
Important warnings
- Estrogen alone increases endometrial cancer risk when the uterus is present.
- May increase risks of blood clots, stroke, heart attack, and dementia in older adults.
- Avoid with unexplained vaginal bleeding, certain cancers, or prior blood clots.
- Report any unusual vaginal bleeding promptly.
Pregnancy
Not used during pregnancy; discontinue if pregnancy occurs.
Breastfeeding
Generally avoided during breastfeeding because it can reduce milk supply.
Interactions
- Some seizure medicines and rifampin can reduce estrogen levels.
- Estrogen may affect thyroid hormone replacement requirements.
- St. John's wort may reduce estrogen effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.