About conestat alfa
Recombinant C1 esterase inhibitor
Used for
- Treats acute hereditary angioedema attacks in adults and adolescents.
Usual adult dose
50 units/kg by intravenous injection; maximum 4,200 units per attack. A second dose may be given if symptoms persist.
Usual dose in children
For adolescents aged 13 and older: 50 units/kg intravenously; maximum 4,200 units per attack. Not established for younger children.
Common side effects
- Headache
- Nausea or diarrhea
- Injection-site reactions
- Allergic reactions, including anaphylaxis
Important warnings
- Use only for hereditary angioedema attacks; it does not prevent attacks.
- Do not use with known or suspected allergy to rabbits or rabbit-derived products.
- Serious allergic reactions can occur; treatment must be given where emergency care is available.
- Not suitable for treating hereditary angioedema attacks in patients with certain C1 inhibitor antibodies.
Pregnancy
Human pregnancy data are limited; use only when clearly needed after weighing potential benefits and risks.
Breastfeeding
It is unknown whether conestat alfa passes into breast milk; consider potential benefits and risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.