About collagenase
Topical enzymatic debriding agent
Used for
- Removes dead tissue from chronic skin ulcers and severe burns to support wound healing.
Usual adult dose
Apply once daily to affected wound tissue; use more often if dressing becomes soiled.
Usual dose in children
Apply once daily to affected wound tissue; pediatric use should be directed by a clinician.
Common side effects
- Temporary irritation or burning at the application site
- Redness or discomfort
Important warnings
- Use only on the wound; avoid contact with eyes.
- Clean the wound as directed before applying.
- Stop if irritation or sensitivity develops.
- Do not use with certain heavy-metal-containing antiseptics, which can reduce activity.
Pregnancy
Adequate studies are lacking; use during pregnancy only when clearly needed.
Breastfeeding
It is not known whether topical collagenase enters breast milk; use caution.
Interactions
- Silver-containing products and some heavy-metal antiseptics may inactivate collagenase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.