About colestyramine
Bile acid sequestrant
Used for
- Lowers high LDL cholesterol.
- Relieves itching caused by bile buildup in some liver conditions.
- Treats bile acid diarrhea, including after some bowel surgery.
Usual adult dose
Usually 4 g once or twice daily; adjusted gradually, up to 24 g daily for cholesterol.
Usual dose in children
For cholesterol in children aged 6–12: usually 4 g once or twice daily; specialist supervision required.
Common side effects
- Constipation
- Bloating or abdominal discomfort
- Nausea
- Can reduce absorption of vitamins A, D, E and K
Important warnings
- Mix powder thoroughly with liquid; do not swallow it dry.
- Take other medicines at least 1 hour before or 4–6 hours after.
- Long-term use may require monitoring of cholesterol and fat-soluble vitamins.
- Avoid or use cautiously with severe constipation or bowel obstruction.
Pregnancy
Not absorbed into the bloodstream, but may reduce vitamin absorption; use only when clinically appropriate.
Breastfeeding
Not absorbed into the bloodstream; may reduce vitamin absorption. Clinical guidance is appropriate during prolonged use.
Interactions
- May reduce absorption of warfarin, thyroid medicines, digoxin, diuretics and many other medicines.
- Separate other medicines by at least 1 hour before or 4–6 hours after.
- May reduce absorption of vitamins A, D, E and K.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.