About coagulation factor viii + von willebrand factor activity
Plasma-derived factor VIII and von Willebrand factor
Used for
- Treatment and prevention of bleeding in von Willebrand disease
- Treatment and prevention of bleeding in hemophilia A
Usual adult dose
Individualized by condition, bleeding severity, body weight, and factor levels; dosing is usually intravenous.
Usual dose in children
Individualized by condition, bleeding severity, body weight, and factor levels; dosing is usually intravenous.
Common side effects
- Headache
- Fever
- Allergic reactions
- Development of inhibitors or antibodies
Important warnings
- Severe allergic reactions can occur.
- Factor VIII inhibitors may reduce treatment effectiveness.
- Thrombosis is possible, especially with high factor levels.
- Use product-specific monitoring and dosing guidance.
Pregnancy
Use when clearly needed; evidence is limited. Bleeding risks and treatment needs require specialist assessment.
Breastfeeding
Information is limited; use requires assessment of treatment benefits and potential risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.