About coagulation factor viii
Human plasma-derived clotting factor VIII
Used for
- Prevention and treatment of bleeding in hemophilia A
- Bleeding control during surgery in hemophilia A
Usual adult dose
Individualized by body weight, bleeding severity, and factor VIII levels; often 20–40 IU/kg for minor bleeding.
Usual dose in children
Individualized by body weight, bleeding severity, and factor VIII levels; dosing is similar to adults.
Common side effects
- Headache
- Fever or chills
- Infusion-site reactions
- Development of factor VIII inhibitors
Important warnings
- Severe allergic reactions can occur.
- Inhibitors may reduce treatment effectiveness.
- Made from human plasma; donor screening and processing reduce, but cannot eliminate, infection risk.
- Use requires monitoring of factor VIII levels and response.
Pregnancy
Human data are limited; use when clearly needed under specialist care.
Breastfeeding
Human data are limited; discuss use with a hemophilia specialist.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.