About coagulati on factor viii
Human blood coagulation factor VIII
Used for
- Treatment and prevention of bleeding in haemophilia A
- Prevention of bleeding during surgery in haemophilia A
Usual adult dose
Individualised by body weight, bleeding severity, factor VIII levels, and clinical response.
Usual dose in children
Individualised by body weight, bleeding severity, factor VIII levels, and clinical response.
Common side effects
- Headache
- Fever
- Injection-site reactions
- Development of factor VIII inhibitors
Important warnings
- Factor VIII inhibitors can reduce or eliminate treatment effectiveness.
- Rare severe allergic reactions, including anaphylaxis, can occur.
- Contains human plasma proteins; a very low risk of infectious-agent transmission remains.
- Administer by intravenous infusion under medical supervision.
Pregnancy
Use only when clearly needed; experience in pregnancy is limited.
Breastfeeding
Use only when clearly needed; data during breastfeeding are limited.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.