About clomethiazole
Sedative-hypnotic; thiamine-related drug
Used for
- Short-term treatment of severe agitation and restlessness in older adults
- Treatment of alcohol withdrawal, including delirium tremens, under medical supervision
- Short-term treatment of severe insomnia in selected patients
Usual adult dose
Doses vary by use and country; alcohol withdrawal requires closely supervised, individualized dosing. Insomnia treatment is generally short term.
Common side effects
- Drowsiness and dizziness
- Nasal irritation or congestion
- Nausea or stomach discomfort
- Confusion and impaired coordination
Important warnings
- Can cause dependence and dangerous withdrawal after regular use.
- Combining with alcohol, opioids, or other sedatives can dangerously suppress breathing.
- Overdose can cause coma, respiratory failure, or death.
- Use requires caution in breathing disorders, liver disease, and older adults.
Pregnancy
Generally avoided unless a specialist judges treatment essential; safety information is limited.
Breastfeeding
Generally avoided because it may sedate the infant; seek specialist guidance.
Interactions
- Alcohol and opioids increase sedation and breathing suppression.
- Benzodiazepines, sleeping tablets, and other sedatives increase respiratory-depression risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.