About clindamycin phosphate + tretinoin
Topical antibiotic and retinoid
Used for
- Treatment of acne vulgaris, including inflamed pimples and blackheads.
Usual adult dose
Apply a thin layer once daily, usually in the evening, to clean, dry acne-affected skin.
Usual dose in children
Not established for children under 12; use in adolescents should follow product labeling.
Common side effects
- Dryness, redness, peeling, or burning at the application site
- Itching or irritation
- Increased sensitivity to sunlight
Important warnings
- Avoid eyes, lips, broken skin, and excessive sunlight.
- Stop and seek medical care for severe or persistent diarrhea; topical clindamycin can rarely cause colitis.
- May worsen irritation when combined with harsh skin products.
- Not for use during pregnancy because tretinoin may harm the fetus.
Pregnancy
Avoid; topical tretinoin is generally not recommended during pregnancy.
Breastfeeding
Use only if prescribed; avoid applying to the breast or areas that may contact the infant.
Interactions
- Other topical acne treatments may increase irritation.
- Avoid combining with products containing erythromycin unless directed by a clinician.
- Neuromuscular-blocking medicines may have enhanced effects with clindamycin, though this is unlikely with topical use.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.