About clevidipine
Intravenous dihydropyridine calcium-channel blocker
Used for
- Rapid blood-pressure reduction when oral treatment is unsuitable
- Perioperative blood-pressure control in adults
Usual adult dose
Start at 1–2 mg/hour; increase as needed, usually up to 16 mg/hour. Higher doses may be used briefly under monitoring.
Common side effects
- Headache
- Nausea and vomiting
- Low blood pressure
- Fast heartbeat
Important warnings
- Requires continuous blood-pressure and heart-rate monitoring.
- Contains soybean oil and egg phospholipids; avoid with relevant allergies.
- Use cautiously with severe aortic stenosis or impaired fat metabolism.
- Not suitable for long-term blood-pressure control; transition to oral treatment when appropriate.
Pregnancy
Human pregnancy data are limited. Use only when clearly needed; untreated severe hypertension also carries risks.
Breastfeeding
It is unknown whether clevidipine enters breast milk. Consider the benefits of treatment and breastfeeding.
Interactions
- Other blood-pressure-lowering medicines may increase the risk of low blood pressure.
- No important CYP-mediated drug interactions are expected.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.