About cladribine
Purine nucleoside antimetabolite
Used for
- Treatment of hairy cell leukemia in adults.
Usual adult dose
Hairy cell leukemia: 0.09 mg/kg/day by continuous intravenous infusion for seven days; oral tablets are not interchangeable with injectable treatment.
Common side effects
- Low blood cell counts
- Fever and infections
- Nausea
- Rash
Important warnings
- Can cause severe, prolonged suppression of blood cell production.
- Serious infections may occur during or after treatment.
- Monitor blood counts and kidney and liver function.
- Avoid live vaccines during treatment and until immune recovery.
Pregnancy
May harm an unborn baby; pregnancy should be avoided during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for one week after the last dose.
Interactions
- Other medicines that suppress bone marrow can increase blood-related toxicity.
- Medicines affecting kidney function may increase toxicity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.