About ciprofloxacine
Fluoroquinolone antibiotic
Used for
- Treats certain serious bacterial infections, including urinary, lung, bone, and skin infections.
- Used when oral treatment is unsuitable or infection requires intravenous therapy.
Usual adult dose
Usually 200–400 mg intravenously every 8–12 hours, adjusted for infection and kidney function.
Usual dose in children
Specialist-directed; typically 10–15 mg/kg intravenously every 8–12 hours, maximum 400 mg per dose.
Common side effects
- Nausea, diarrhoea, or vomiting
- Pain or inflammation at the infusion site
- Dizziness, headache, or sleep disturbance
- Tendon inflammation or rupture; nerve symptoms
Important warnings
- Use only for susceptible bacterial infections; resistance can develop.
- Stop and seek prompt medical assessment for tendon pain, severe allergy, or nerve symptoms.
- May worsen myasthenia gravis; use caution with seizure disorders and heart-rhythm problems.
- Kidney impairment may require dose adjustment; maintain adequate hydration.
Pregnancy
Generally avoided unless a clinician determines it is essential; human pregnancy data are limited.
Breastfeeding
Ciprofloxacin enters breast milk. Use requires clinical assessment; monitor the infant for diarrhoea or thrush.
Interactions
- Tizanidine: combination is contraindicated because ciprofloxacin can greatly increase its effects.
- Warfarin: may increase bleeding risk; closer monitoring may be needed.
- Medicines that prolong the QT interval can increase abnormal heart-rhythm risk.
- Theophylline and some diabetes medicines may have increased effects or side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.