About ciclo spori n
Calcineurin inhibitor immunosuppressant
Used for
- Prevention of organ transplant rejection
- Treatment of severe rheumatoid arthritis
- Treatment of severe psoriasis
- Treatment of certain inflammatory eye diseases
Usual adult dose
Varies by condition and body weight; transplant doses are individualized and closely monitored.
Usual dose in children
For transplant rejection prevention, usually 10–15 mg/kg daily in two divided doses initially; specialist-adjusted.
Common side effects
- Kidney problems and high blood pressure
- Tremor, headache, or increased hair growth
- Increased risk of infections and some cancers
- Nausea, diarrhea, or swollen gums
Important warnings
- Requires regular blood tests, including kidney function and drug levels.
- Do not substitute formulations without medical supervision; absorption can differ.
- Avoid grapefruit and grapefruit juice.
- Increased infection and skin-cancer risk; limit sun exposure.
Pregnancy
May be used when necessary under specialist care; risks and benefits require assessment.
Breastfeeding
Use only after specialist assessment; cyclosporine enters breast milk.
Interactions
- Many interactions, including with some antibiotics, antifungals, seizure medicines, and HIV medicines.
- Statins can increase muscle injury risk; digoxin and colchicine levels may rise.
- Avoid potassium supplements or potassium-sparing medicines unless specifically directed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.