About cholestyramine resin
Bile acid sequestrant
Used for
- Lowers high cholesterol, especially LDL cholesterol.
- Relieves itching caused by partial bile-duct blockage.
- Treats bile-acid diarrhea, including after gallbladder surgery.
Usual adult dose
High cholesterol: usually 4 g once or twice daily, adjusted gradually; maximum 24 g daily. Other uses vary.
Usual dose in children
High cholesterol: usually 240 mg/kg daily in divided doses; maximum 8 g daily for ages 6–12. Specialist dosing is required.
Common side effects
- Constipation
- Bloating or gas
- Nausea
- May reduce absorption of vitamins A, D, E, and K
Important warnings
- Separate other medicines by at least 1 hour before or 4–6 hours after.
- May worsen severe constipation or bowel obstruction.
- Long-term use may impair absorption of fat-soluble vitamins.
- Mix powder thoroughly with liquid; never swallow it dry.
Pregnancy
Not absorbed into the bloodstream, but may reduce absorption of fat-soluble vitamins; use requires clinical assessment.
Breastfeeding
Not absorbed into the bloodstream; reduced vitamin absorption may be relevant during breastfeeding.
Interactions
- Can reduce absorption of many medicines, including warfarin, thyroid medicines, and some antibiotics.
- May reduce absorption of fat-soluble vitamins.
- May increase triglycerides in some people.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.