About chlorprothixene
First-generation thioxanthene antipsychotic
Used for
- Schizophrenia and other psychotic disorders
- Agitation or restlessness, where prescribed
Usual adult dose
Psychosis: usually 50–100 mg daily initially, adjusted gradually; doses vary by condition and country.
Common side effects
- Sleepiness, dizziness, and slowed reactions
- Dry mouth, constipation, or blurred vision
- Weight gain and low blood pressure on standing
- Movement problems, including tremor or stiffness
Important warnings
- Can impair alertness; avoid driving if affected.
- May cause abnormal heart rhythms, especially with other risk factors.
- Seek urgent care for high fever, severe stiffness, or confusion.
- Do not stop suddenly without medical guidance.
Pregnancy
Use only when considered necessary; late-pregnancy exposure may cause symptoms in newborns.
Breastfeeding
May cause sleepiness or other effects in the infant; clinical guidance is needed.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness.
- Medicines that prolong the QT interval may increase heart-rhythm risks.
- Levodopa and dopamine medicines may work less effectively.
- Other antipsychotics or blood-pressure medicines may increase side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.