About chlorothiazide
Thiazide diuretic
Used for
- Short-term treatment of fluid buildup when oral medicines are unsuitable
- Management of high blood pressure when oral treatment is unsuitable
Usual adult dose
Usually 500 mg to 1 g by slow intravenous injection once or twice daily; dose depends on response.
Usual dose in children
Not routinely used in children; specialist dosing is required.
Common side effects
- Low potassium or sodium
- Dizziness or low blood pressure
- High blood sugar
- Nausea or diarrhea
Important warnings
- Monitor fluid levels, electrolytes, kidney function, and blood pressure.
- Use caution with kidney or liver disease, gout, and diabetes.
- Avoid in anuria or severe sulfonamide allergy.
- This injection is for healthcare professionals; route and preparation depend on product instructions.
Pregnancy
Use only when clearly needed; thiazides may affect placental blood flow and fetal or newborn fluid balance.
Breastfeeding
Use caution: thiazides can enter milk and may reduce milk production, particularly at higher doses.
Interactions
- Lithium: may increase lithium levels and toxicity.
- Digoxin: low potassium can increase risk of abnormal heart rhythms.
- NSAIDs may reduce diuretic and blood-pressure effects.
- Corticosteroids or stimulant laxatives may increase potassium loss.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.