About chloroquine sulfate
Antimalarial; antiprotozoal
Used for
- Treatment of malaria caused by chloroquine-sensitive parasites; injection is generally reserved for severe illness when oral treatment is unsuitable.
Usual adult dose
For severe malaria, dosing is weight-based and given by slow intravenous infusion under hospital monitoring; regimens vary by local guidelines.
Usual dose in children
For severe malaria, weight-based dosing is given by slow intravenous infusion under hospital monitoring; regimens vary by local guidelines.
Common side effects
- Nausea and vomiting
- Headache and dizziness
- Low blood pressure or heart rhythm disturbances
- Seizures or low blood sugar
Important warnings
- Injection can cause severe, potentially fatal heart and breathing problems if given too rapidly.
- Use only under close medical monitoring; follow the specific product and local malaria guidelines.
- Chloroquine-resistant malaria is common; treatment depends on parasite sensitivity.
- Use cautiously with heart rhythm disorders, epilepsy, or liver or kidney problems.
Pregnancy
Malaria can be dangerous during pregnancy. Chloroquine may be used for sensitive malaria when clinically indicated; treatment choice depends on resistance and severity.
Breastfeeding
Small amounts enter breast milk; breastfeeding is generally compatible, but milk exposure does not treat or prevent malaria in the infant.
Interactions
- Medicines that prolong the QT interval can increase dangerous heart rhythm risk.
- Amiodarone and other antiarrhythmics may increase cardiac risk.
- Cimetidine can increase chloroquine levels.
- Antacids may reduce absorption of oral chloroquine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.