About chlorambucil
Alkylating chemotherapy medicine
Used for
- Chronic lymphocytic leukaemia
- Hodgkin lymphoma
- Certain non-Hodgkin lymphomas
Usual adult dose
Varies by cancer and treatment plan; specialist-prescribed, often given daily or in treatment cycles.
Usual dose in children
Specialist-prescribed for selected cancers; dose is based on body surface area and treatment plan.
Common side effects
- Low blood cell counts and increased infection risk
- Nausea, vomiting, or diarrhoea
- Mouth sores
- Infertility or absent menstrual periods
Important warnings
- Can cause severe bone marrow suppression and serious infections.
- Can cause seizures, especially with high doses or in children.
- May increase risk of later cancers and affect fertility.
- Requires regular blood tests and specialist supervision.
Pregnancy
May harm an unborn baby. Avoid during pregnancy unless a specialist determines it is essential.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Other medicines that suppress bone marrow can increase blood-cell problems.
- Live vaccines may cause infection and should generally be avoided during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.