About chenodeoycholic acid
Primary bile acid; bile acid replacement
Used for
- Treatment of cerebrotendinous xanthomatosis (CTX), a rare inherited metabolic disorder.
Usual adult dose
CTX: usually 750 mg daily, divided into three doses; specialist-adjusted.
Usual dose in children
CTX: usually 15 mg/kg daily in three divided doses; specialist-adjusted.
Common side effects
- Diarrhea
- Abdominal discomfort
- Nausea
Important warnings
- Monitor liver function and blood cholesterol during treatment.
- Use specialist supervision; dosing may require adjustment based on response and laboratory tests.
- Gallstone-dissolving use is uncommon and requires medical supervision.
Pregnancy
Limited safety information; treatment decisions require specialist assessment of maternal and fetal risks.
Breastfeeding
Limited information; specialist assessment is needed before use while breastfeeding.
Interactions
- Bile acid-binding medicines, such as cholestyramine, can reduce absorption; separate doses.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.