About certolizum ab pegol
TNF-alpha inhibitor biologic
Used for
- Rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
- Non-radiographic axial spondyloarthritis
- Plaque psoriasis
- Crohn’s disease in some countries
Usual adult dose
Usually 400 mg under the skin initially, then 200 mg every two weeks or 400 mg every four weeks, depending on the condition.
Common side effects
- Upper respiratory infections
- Injection-site reactions
- Rash
- Headache
Important warnings
- Serious infections, including tuberculosis, can occur.
- May reactivate hepatitis B; screening is recommended before treatment.
- Avoid live vaccines during treatment.
- Rarely, can worsen heart failure or cause serious blood disorders.
Pregnancy
May be used when needed; discuss risks with a clinician. It has minimal transfer across the placenta.
Breastfeeding
Usually considered compatible; very small amounts are expected in breast milk.
Interactions
- Other biologic immune suppressants, including anakinra or abatacept, may increase serious infection risk.
- Live vaccines may cause infection during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.