About cephaloridin
First-generation cephalosporin antibiotic
Used for
- Susceptible bacterial respiratory infections
- Susceptible bacterial urinary tract infections
- Susceptible bacterial skin and soft tissue infections
Usual adult dose
Historically, 1–3 g daily by injection, divided into 2–3 doses. Doses require reduction with impaired kidney function.
Usual dose in children
Historically, 25–50 mg/kg daily by injection, divided into 2–3 doses.
Common side effects
- Kidney damage
- Allergic reactions, including severe reactions
- Diarrhea, nausea, or vomiting
- Pain at the injection site
Important warnings
- Largely replaced by safer antibiotics because of kidney toxicity
- Kidney function monitoring is essential
- Serious allergic reactions possible with cephalosporin or penicillin allergy
- Severe or persistent diarrhea may indicate antibiotic-associated colitis
Pregnancy
Specific pregnancy safety data are limited. Historically used when the expected benefit justified potential risks.
Breastfeeding
Breastfeeding data are limited. Possible infant effects include diarrhea, thrush, or allergic reactions.
Interactions
- Aminoglycoside antibiotics increase kidney damage risk
- Loop diuretics, including furosemide, increase kidney damage risk
- Other kidney-toxic medicines increase kidney damage risk
- Probenecid may increase antibiotic blood levels
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.