About cefuroxime sodium
Second-generation cephalosporin antibiotic
Used for
- Treatment of susceptible bacterial infections, including respiratory, urinary, skin, and bone infections
- Prevention of infection during certain surgeries
Usual adult dose
Usually 750 mg to 1.5 g by injection every 6–8 hours, depending on infection.
Usual dose in children
Usually 30–100 mg/kg/day by injection, divided every 6–8 hours; varies by infection.
Common side effects
- Injection-site pain or inflammation
- Diarrhea, nausea, or vomiting
- Rash or itching
- Changes in blood counts or liver tests
Important warnings
- Do not use with serious allergy to cefuroxime or other cephalosporins.
- Tell clinicians about severe penicillin or other beta-lactam allergies.
- Antibiotic-associated severe diarrhea can occur during or after treatment.
- Dose adjustment may be needed with kidney problems.
Pregnancy
Use when clinically indicated; available evidence has not shown a clear increase in major birth defects.
Breastfeeding
Small amounts may enter breast milk; usually compatible, but infant diarrhea or thrush may occur.
Interactions
- Probenecid can increase cefuroxime levels.
- Medicines that may harm the kidneys can increase kidney-related risks.
- Some laboratory glucose tests may give misleading results.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.