About ceftriaxone sodium
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, and bloodstream infections.
- Treats gonorrhea and certain infections of the skin, bones, abdomen, or urinary tract.
- Prevents infection around some operations.
Usual adult dose
Usually 1–2 g by injection once daily; some infections require higher or divided doses.
Usual dose in children
Usually 50–75 mg/kg by injection daily; meningitis often requires 100 mg/kg daily. Maximum doses depend on infection.
Common side effects
- Diarrhea, nausea, or rash
- Pain or swelling at injection site
- Changes in blood counts or liver tests
- Rare severe allergic reactions or antibiotic-associated colitis
Important warnings
- Avoid with serious allergy to ceftriaxone or other cephalosporins.
- Seek urgent care for breathing difficulty, facial swelling, or severe skin reactions.
- Newborns with jaundice or receiving intravenous calcium may be at risk of serious harm.
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
Pregnancy
Generally considered usable when needed; treatment depends on the infection and clinical circumstances.
Breastfeeding
Usually compatible; monitor for infant diarrhea, thrush, or rash.
Interactions
- Calcium-containing intravenous solutions can interact, especially in newborns.
- Warfarin may have stronger effects; monitoring may be needed.
- Probenecid can affect ceftriaxone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.