About ceftriaxone sodium
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, and bloodstream infections
- Treats gonorrhea and some skin, urinary, bone, or joint infections
Usual adult dose
Usually 1–2 g by injection once daily; dose and duration depend on infection.
Usual dose in children
Usually 50–75 mg/kg by injection once daily; meningitis may require 100 mg/kg daily, up to 4 g.
Common side effects
- Diarrhea, nausea, or rash
- Pain or swelling at injection site
- Changes in blood counts or liver tests
- Severe allergic reactions, rarely
Important warnings
- Use only for bacterial infections; unnecessary use promotes resistance.
- Avoid with serious cephalosporin allergy; discuss penicillin allergy with a clinician.
- Do not mix or administer with calcium-containing IV solutions in newborns.
- Seek urgent care for severe diarrhea, breathing difficulty, or widespread rash.
Pregnancy
Generally considered usable when clinically needed; evidence has not shown a clear major birth-defect risk.
Breastfeeding
Usually compatible; small amounts enter milk. Monitor for infant diarrhea or thrush.
Interactions
- Warfarin: may increase bleeding risk; monitoring may be needed.
- Calcium-containing IV solutions: dangerous precipitation risk in newborns.
- Probenecid may alter ceftriaxone handling; clinical importance is uncertain.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.