About ceftriaxon e m + vial
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, bloodstream, urinary, and skin infections.
- Used for gonorrhea and certain infections before surgery.
Usual adult dose
Usually 1–2 g once daily by injection; some severe infections need up to 4 g daily, divided.
Usual dose in children
Usually 50–75 mg/kg once daily; meningitis may require 100 mg/kg daily, up to 4 g.
Common side effects
- Diarrhea, nausea, or rash
- Pain or inflammation at the injection site
- Changes in blood counts or liver tests
- Rare severe allergic reactions or antibiotic-associated bowel inflammation
Important warnings
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
- Avoid with serious allergy to ceftriaxone or other cephalosporins; discuss severe penicillin allergy.
- Newborns with jaundice or receiving intravenous calcium may face serious risks.
- Dose and duration depend on infection, age, kidney and liver function.
Pregnancy
Generally used when needed; available evidence has not shown a clear increased risk of birth defects.
Breastfeeding
Usually compatible; small amounts enter milk. Monitor infants for diarrhea, thrush, or rash.
Interactions
- Calcium-containing intravenous solutions can form dangerous precipitates, especially in newborns.
- May increase bleeding risk with warfarin; monitoring may be needed.
- Chloramphenicol may reduce antibiotic activity in laboratory studies.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.