About ceftriaxon e m
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, bloodstream, urinary, and skin infections.
- May be used before certain surgeries to prevent infection.
Usual adult dose
Usually 1–2 g once daily; some severe infections require up to 4 g daily, divided doses, by injection.
Usual dose in children
Usually 50–75 mg/kg daily; meningitis may require 100 mg/kg daily, maximum 4 g.
Common side effects
- Injection-site pain
- Diarrhea or nausea
- Rash
- Changes in blood counts or liver tests
Important warnings
- Not for viral infections such as colds or flu.
- Serious allergic reactions can occur, especially with cephalosporin allergy.
- Use caution with severe penicillin allergy and in newborns with jaundice or intravenous calcium treatment.
- Antibiotic-associated severe diarrhea can occur during or after treatment.
Pregnancy
Generally used when clinically needed; pregnancy-specific assessment is appropriate.
Breastfeeding
Usually compatible; monitor infants for diarrhea, thrush, or rash.
Interactions
- Warfarin: may increase bleeding risk; monitoring may be needed.
- Calcium-containing intravenous solutions must not be mixed with ceftriaxone, especially in newborns.
- Probenecid may affect ceftriaxone elimination.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.