About ceftobiprole
Intravenous fifth-generation cephalosporin antibiotic
Used for
- Treats community-acquired pneumonia in adults
- Treats hospital-acquired pneumonia in adults, excluding ventilator-associated pneumonia
Usual adult dose
500 mg intravenously every 8 hours, infused over 2 hours; dose adjustment is needed with kidney impairment.
Common side effects
- Nausea, diarrhea, or vomiting
- Rash or itching
- Headache
- Abnormal liver blood tests
Important warnings
- Serious allergic reactions can occur, especially with cephalosporin or penicillin allergy.
- Antibiotics may cause severe, persistent diarrhea from Clostridioides difficile.
- Dose adjustment is needed for reduced kidney function.
- Use only for susceptible bacterial infections; it does not treat viral illnesses.
Pregnancy
Human pregnancy data are limited; use when clearly needed after weighing potential benefits and risks.
Breastfeeding
It is not known whether ceftobiprole passes into breast milk; consider potential infant exposure and effects.
Interactions
- Probenecid can increase ceftobiprole exposure; combined use is generally avoided.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.