About ceftazidime pentahydrate
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, blood, bone, urinary, and skin infections.
- May treat meningitis and infections caused by susceptible bacteria, including Pseudomonas.
Usual adult dose
Usually 1–2 g intravenously or intramuscularly every 8–12 hours; dose depends on infection and kidney function.
Usual dose in children
Usually 30–50 mg/kg intravenously every 8 hours; specialist dosing depends on age, infection, and kidney function.
Common side effects
- Diarrhea, nausea, or vomiting
- Injection-site pain or inflammation
- Rash or itching
- Changes in blood counts or liver tests
Important warnings
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
- Dose adjustment is needed with impaired kidney function.
- Seek urgent care for severe allergic reactions or severe, persistent diarrhea.
- Tell clinicians about severe penicillin or cephalosporin allergy.
Pregnancy
May be used when clinically necessary; a clinician should weigh benefits and risks.
Breastfeeding
Usually compatible; monitor the infant for diarrhea, rash, or thrush.
Interactions
- Probenecid may increase ceftazidime levels.
- Other medicines that can affect the kidneys may increase kidney-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.