About ceftazidime
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, bloodstream, urinary, and bone infections.
- Treats infections caused by susceptible bacteria, including Pseudomonas aeruginosa.
Usual adult dose
Usually 1–2 g intravenously or intramuscularly every 8–12 hours; dose varies with infection and kidney function.
Usual dose in children
Usually 30–50 mg/kg intravenously every 8 hours; maximum 6 g daily. Newborn doses and schedules differ.
Common side effects
- Diarrhea, nausea, or vomiting
- Injection-site pain or inflammation
- Rash or itching
- Abnormal blood counts or liver tests
Important warnings
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
- Dose adjustment is often needed in kidney impairment.
- Seek urgent care for severe allergic reactions or severe, persistent diarrhea.
- Seizures or confusion can occur, especially with high doses or kidney impairment.
Pregnancy
May be used during pregnancy when clinically appropriate; human safety data are limited.
Breastfeeding
Small amounts may enter breast milk; infant diarrhea or thrush is possible.
Interactions
- Probenecid may increase ceftazidime levels.
- Aminoglycoside antibiotics or potent diuretics may increase kidney-injury risk.
- Warfarin may have increased anticoagulant effects; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.