About cefotaxime sodium iv
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, bloodstream, urinary, and abdominal infections.
- Prevents infection during some surgical procedures.
Usual adult dose
Commonly 1–2 g intravenously every 8–12 hours; severe infections may require higher or more frequent doses, up to 12 g daily.
Usual dose in children
Typically 50–150 mg/kg/day intravenously, divided every 6–12 hours; meningitis may require up to 200 mg/kg/day.
Common side effects
- Diarrhea, nausea, or vomiting
- Injection-site pain or inflammation
- Rash or allergic reactions
- Changes in blood counts or liver tests
Important warnings
- Use only for susceptible bacterial infections; it does not treat viral infections.
- Adjust dosing in significant kidney impairment.
- Seek urgent care for severe allergy or persistent, severe, or bloody diarrhea.
- People with serious penicillin or cephalosporin allergy may have reactions.
Pregnancy
May be used when clinically needed; pregnancy-specific assessment is appropriate.
Breastfeeding
Small amounts may enter breast milk; monitor for infant diarrhea, thrush, or rash.
Interactions
- Probenecid can increase cefotaxime levels.
- Aminoglycoside antibiotics or potent diuretics may increase kidney-toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.