About cefotaxime m
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia, meningitis, and bloodstream infections.
- May prevent infections during certain operations.
Usual adult dose
Usually 1–2 g intravenously or into a muscle every 8–12 hours; severe infections may need higher doses.
Usual dose in children
Usually 50–180 mg/kg daily intravenously or into a muscle, divided into 4–6 doses; meningitis often requires higher doses.
Common side effects
- Diarrhea, nausea, or vomiting
- Pain or inflammation at the injection site
- Rash or allergic reactions
- Changes in blood counts or liver tests
Important warnings
- Not effective against viral infections.
- Serious allergic reactions can occur, especially with cephalosporin or penicillin allergy.
- Antibiotic-associated severe diarrhea may occur during treatment or afterward.
- Dose adjustment may be needed with kidney impairment.
Pregnancy
Can be used when clinically needed; available evidence has not identified a clear risk to the fetus.
Breastfeeding
Usually compatible; small amounts may enter milk and occasionally affect an infant’s digestion or cause thrush.
Interactions
- Probenecid can increase cefotaxime levels.
- Other medicines that can harm the kidneys may increase kidney-related risks.
- Warfarin may require closer monitoring of blood clotting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.