About cefepime dihydrochloride monohydrate m
Fourth-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia and urinary infections.
- Treats skin, abdominal, and bloodstream infections.
- May treat fever in people with low white blood cell counts.
Usual adult dose
Usually 1–2 g intravenously every 8–12 hours; dose and interval depend on infection and kidney function.
Usual dose in children
Usually 50 mg/kg intravenously every 8–12 hours; maximum 2 g per dose. Dosing depends on age, infection, and kidney function.
Common side effects
- Diarrhea, nausea, or vomiting
- Rash or itching
- Injection-site reactions
- Confusion or seizures, especially with kidney problems or excessive dosing
Important warnings
- Use only for infections caused by susceptible bacteria; it does not treat viral infections.
- Dose adjustment is usually needed with reduced kidney function.
- Seek urgent care for severe allergic reactions or severe, persistent diarrhea.
- Neurological effects, including seizures, can occur, particularly if doses accumulate.
Pregnancy
Available evidence has not shown clear harm, but use during pregnancy requires clinical assessment.
Breastfeeding
Small amounts may enter breast milk; monitor for infant diarrhea, thrush, or rash.
Interactions
- Aminoglycoside antibiotics or potent diuretics may increase kidney injury risk.
- Warfarin may have an increased effect; monitoring may be needed.
- Other antibiotics may alter its effect or increase side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.