About cefepime
Fourth-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia and urinary infections
- Treats skin and abdominal infections caused by susceptible bacteria
- Treats febrile neutropenia and some bloodstream infections
Usual adult dose
Usually 1–2 g intravenously every 8–12 hours, adjusted for infection and kidney function.
Usual dose in children
Usually 50 mg/kg intravenously every 8–12 hours; maximum 2 g per dose. Dose depends on age, infection, and kidney function.
Common side effects
- Diarrhea, nausea, or rash
- Injection-site reactions
- Allergic reactions
- Confusion or seizures, especially with kidney impairment
Important warnings
- Kidney impairment requires dose adjustment
- Serious allergy may occur, particularly with cephalosporin or penicillin allergy
- Cefepime-associated seizures and confusion can occur, especially if doses are not adjusted
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance
Pregnancy
Use when clinically needed; human pregnancy data are limited.
Breastfeeding
Small amounts may enter breast milk; monitor the infant for diarrhea or thrush.
Interactions
- Aminoglycoside antibiotics may increase kidney or hearing toxicity
- Strong diuretics may increase kidney toxicity risk
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.