About cefaclor as monohydr
Second-generation cephalosporin antibiotic
Used for
- Bacterial ear infections
- Bacterial respiratory tract infections
- Bacterial urinary tract infections
- Bacterial skin infections
Usual adult dose
Usually 250 mg every 8 hours; severe infections may require 500 mg every 8 hours. Duration depends on infection.
Usual dose in children
Children over 1 month: 20 mg/kg/day divided every 8 hours; severe infections: 40 mg/kg/day. Maximum 1 g/day.
Common side effects
- Diarrhea
- Nausea or vomiting
- Skin rash
- Thrush
Important warnings
- Avoid with known cefaclor or cephalosporin allergy.
- Serious allergic reactions can occur, including with previous penicillin allergy.
- Severe or persistent diarrhea may indicate antibiotic-associated colitis.
- Fever, rash, and joint pain may indicate serum sickness-like reaction.
Pregnancy
Available evidence suggests low risk; use during pregnancy when clinically needed.
Breastfeeding
Small amounts enter breast milk; generally compatible. Infants may develop diarrhea or thrush.
Interactions
- Warfarin: may increase bleeding risk.
- Probenecid: increases cefaclor levels.
- Live oral typhoid vaccine: may reduce vaccine effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.