About catumaxomab
Trifunctional monoclonal antibody
Used for
- Treatment of malignant ascites in adults with EpCAM-positive cancers when standard treatment is unavailable or unsuitable.
Usual adult dose
Given as four intraperitoneal infusions over about 10 days: 10, 20, 50, then 150 micrograms.
Common side effects
- Fever, chills, nausea, and vomiting
- Abdominal pain
- Low blood-cell counts
- Liver-enzyme changes
Important warnings
- Administered into the abdominal cavity by experienced clinicians.
- Can cause serious infusion reactions, including breathing problems and low blood pressure.
- Monitor for severe inflammatory reactions and liver problems.
- Use only when the tumor expresses EpCAM.
Pregnancy
Pregnancy safety is not established; use during pregnancy is generally avoided unless clearly necessary.
Breastfeeding
It is not known whether catumaxomab passes into breast milk; breastfeeding considerations require specialist review.
Interactions
- No well-established specific medicine interactions; effects of immune-modulating treatments may need consideration.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.