About caspofungin acetate
Echinocandin antifungal
Used for
- Treatment of invasive Candida infections, including candidemia
- Treatment of invasive Aspergillus infections when other treatments fail or are not tolerated
- Empiric treatment of suspected fungal infections in febrile patients with low white blood cells
Usual adult dose
Usually 70 mg intravenously once on day one, then 50 mg once daily; some infections require 70 mg daily.
Usual dose in children
For ages 3 months to 17 years: 70 mg/m² intravenously on day one, then 50 mg/m² daily; maximum 70 mg daily.
Common side effects
- Fever
- Diarrhea
- Nausea or vomiting
- Infusion reactions, including rash or facial swelling
Important warnings
- Given by intravenous infusion by a healthcare professional.
- Serious allergic or infusion reactions can occur.
- Liver problems may require monitoring or dose adjustment.
- Dose adjustment may be needed with certain medicines or liver impairment.
Pregnancy
Human pregnancy information is limited; use only when the expected benefit outweighs potential risk.
Breastfeeding
It is unknown whether caspofungin passes into breast milk; discuss risks and benefits with a healthcare professional.
Interactions
- Rifampin and some other enzyme-inducing medicines may reduce caspofungin levels.
- Cyclosporine may increase liver enzyme levels with caspofungin.
- Caspofungin may lower tacrolimus levels; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.