About canagliflo zin
Sodium-glucose cotransporter-2 inhibitor
Used for
- Type 2 diabetes, alongside diet and exercise
- Reducing cardiovascular and kidney complications in some adults with type 2 diabetes
Usual adult dose
Usually 100 mg once daily before the first meal; may increase to 300 mg daily if kidney function permits.
Common side effects
- Genital yeast infections
- Increased urination
- Dehydration or low blood pressure
- Urinary infections
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis
- Rarely causes ketoacidosis, sometimes with near-normal blood sugar
- May increase risk of serious genital infection or lower-limb amputation
- Dose suitability depends on kidney function
Pregnancy
Avoid during pregnancy, especially later pregnancy, because of potential harm to fetal kidney development.
Breastfeeding
Not recommended while breastfeeding; effects on a nursing infant are uncertain.
Interactions
- Insulin or sulfonylureas may increase low blood sugar risk
- Diuretics may increase dehydration and low blood pressure
- Rifampin may reduce canagliflozin levels
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.