About calcium polystryene sulfonate
Potassium-binding cation-exchange resin
Used for
- Treats high blood potassium (hyperkalaemia).
Usual adult dose
Usually 15 g by mouth three or four times daily; rectal dosing is also used.
Usual dose in children
Dose is based on body weight and blood potassium; specialist guidance is required.
Common side effects
- Constipation
- Nausea or vomiting
- Low blood potassium
- Low blood calcium or magnesium
Important warnings
- Can cause severe constipation, bowel blockage, or rarely bowel injury.
- Avoid in bowel obstruction or significantly impaired bowel movement.
- Separate from other oral medicines by at least three hours.
- Blood potassium and other electrolytes need monitoring.
Pregnancy
May be used when needed under medical supervision; pregnancy-specific evidence is limited.
Breastfeeding
Likely compatible because it is not absorbed significantly; clinical evidence is limited.
Interactions
- May reduce absorption of other oral medicines; separate doses by at least three hours.
- Sorbitol increases the risk of serious bowel injury and should be avoided.
- May reduce absorption of lithium or levothyroxine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.