About caffine citrate each
Central nervous system stimulant
Used for
- Treats pauses in breathing in premature babies
Usual adult dose
No established usual adult dose for this use.
Usual dose in children
Premature babies: 20 mg/kg caffeine citrate loading dose, then 5 mg/kg once daily, starting 24 hours later; given orally or intravenously.
Common side effects
- Fast heartbeat
- Restlessness or jitteriness
- Feeding intolerance or vomiting
- Increased urination
Important warnings
- Requires specialist supervision and monitoring in premature babies
- Use cautiously with seizures or heart rhythm problems
- Other causes of breathing pauses must be excluded
- Caffeine citrate and caffeine base doses are not interchangeable
Pregnancy
Caffeine crosses the placenta. Safety of medicinal caffeine citrate during pregnancy is not established.
Breastfeeding
Caffeine passes into breast milk and may cause infant irritability or poor sleep, particularly in premature babies.
Interactions
- Theophylline may increase caffeine exposure and stimulant effects
- Other stimulants may increase heartbeat and restlessness
- Cimetidine may reduce caffeine clearance
- Phenytoin may increase caffeine clearance
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.