About caffeine + carbinoxamine + codeine + acetaminophen + phenylephrine
Combination cold and cough medicine
Used for
- Temporarily relieves pain, fever, nasal congestion, runny nose, and cough associated with colds.
Usual adult dose
Dosing varies by product; follow the package directions. Do not exceed the stated daily limit.
Usual dose in children
Not appropriate for children under 12. For ages 12–17, use only if specifically directed by a clinician.
Common side effects
- Drowsiness, dizziness, or impaired coordination
- Nausea, constipation, or dry mouth
- Restlessness, trouble sleeping, or fast heartbeat
Important warnings
- Codeine can slow or stop breathing and can cause dependence; avoid alcohol and sedatives.
- Do not combine with other acetaminophen-containing medicines; overdose can severely damage the liver.
- Carbinoxamine may cause marked drowsiness; avoid driving until effects are known.
- Avoid in children under 12; codeine cough medicines are not recommended for adolescents with breathing problems.
Pregnancy
Avoid unless a clinician determines it is necessary. Codeine and other ingredients may pose risks during pregnancy.
Breastfeeding
Not recommended; codeine and carbinoxamine may harm or sedate a nursing infant and reduce milk supply.
Interactions
- Alcohol, opioids, sleeping pills, and sedatives increase breathing and drowsiness risks.
- MAO inhibitors and some antidepressants may cause serious interactions.
- Other acetaminophen products increase liver-damage risk.
- Stimulants and decongestants may worsen high blood pressure or fast heartbeat.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.