About cabazitaxel
Taxane chemotherapy medicine
Used for
- Treats advanced prostate cancer that has spread despite hormone treatment, usually with prednisone.
Usual adult dose
Usual dose is 20 mg/m² by intravenous infusion every three weeks, with prednisone; some patients receive 25 mg/m².
Common side effects
- Low blood cell counts and increased infection risk
- Diarrhea, nausea, vomiting, or constipation
- Fatigue, weakness, or loss of appetite
- Kidney problems or allergic reactions
Important warnings
- Can cause severe infections, low blood counts, and life-threatening complications.
- Requires preventive medicines and blood-count monitoring; treatment is supervised by cancer specialists.
- Tell the care team about fever, severe diarrhea, or allergic symptoms promptly.
- Not suitable for severe liver impairment; avoid live vaccines during treatment.
Pregnancy
May harm an unborn baby. Men and women should use effective contraception during treatment; men should continue for three months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for two months after the final dose.
Interactions
- Strong CYP3A inhibitors, such as clarithromycin, may increase cabazitaxel effects.
- Strong CYP3A inducers, such as rifampicin, may reduce its effects.
- Tell the care team about anticoagulants and other medicines affecting blood counts or infection risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.