About c inhibitor
Plasma-derived C1 esterase inhibitor
Used for
- Prevention of hereditary angioedema attacks in adults and children
- Treatment of acute hereditary angioedema attacks in adults and children
- Prevention of hereditary angioedema attacks before medical, dental, or surgical procedures
Usual adult dose
Prevention: 1,000 IU intravenously every 3–4 days. Acute attack: 1,000 IU intravenously; a second dose may be given after one hour if needed.
Usual dose in children
Prevention, ages 6–11: 500 IU intravenously every 3–4 days. Acute attack: 500 IU; a second dose may be given after one hour if needed. Under age 6: dosing is individualized.
Common side effects
- Headache
- Nausea
- Rash
- Injection-site reactions
Important warnings
- Serious allergic reactions, including anaphylaxis, can occur.
- Blood clots have been reported, especially with risk factors or high doses.
- As a human blood product, it may carry a very small risk of infection transmission.
- Not effective for hereditary angioedema attacks involving the larynx; urgent airway care may be needed.
Pregnancy
Human pregnancy data are limited; use when clinically needed after weighing potential benefits and risks.
Breastfeeding
It is not known whether the medicine enters breast milk; consider clinical need and potential infant exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.