About bulevirtide
Hepatitis D virus entry inhibitor
Used for
- Treats chronic hepatitis D infection in adults with compensated liver disease.
Usual adult dose
2 mg injected under the skin once daily.
Common side effects
- Headache
- Injection-site reactions
- Raised bile acids
- Fatigue
Important warnings
- Use only for chronic hepatitis D with compensated liver disease.
- Stopping treatment can cause hepatitis to flare; monitor liver tests.
- Raised bile acids are common and may cause itching.
- Treatment may reactivate hepatitis B; monitor for changes.
Pregnancy
Human pregnancy data are limited; use only when clearly needed after clinical assessment.
Breastfeeding
It is unknown whether bulevirtide passes into breast milk; effects on infants are unknown.
Interactions
- Medicines that block bile salt transporters, such as cyclosporine, may increase bile acids.
- OATP1B1/3 transporter inhibitors, including rifampicin, may affect bulevirtide exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.