About bortezomi b + vial
Proteasome inhibitor anticancer medicine
Used for
- Treats multiple myeloma, often with other cancer medicines.
- Treats mantle cell lymphoma, usually with other cancer medicines.
Usual adult dose
Given by a specialist as an injection into a vein or under the skin; dosing depends on the regimen and treatment cycle.
Common side effects
- Low blood cell counts, increasing infection or bleeding risk
- Nerve damage causing numbness, tingling, or pain
- Nausea, diarrhea, constipation, or vomiting
- Fatigue, fever, or shingles
Important warnings
- Can cause serious nerve damage, low blood counts, or lung and heart problems.
- May reactivate hepatitis B; screening and monitoring may be needed.
- Can cause fetal harm; pregnancy must be avoided during treatment.
- Treatment requires specialist monitoring and blood tests.
Pregnancy
Can harm an unborn baby. Avoid pregnancy during treatment; follow the specialist’s guidance on contraception and timing after treatment.
Breastfeeding
Breastfeeding is not recommended during treatment and for two months after the final dose.
Interactions
- Strong CYP3A4 inhibitors may increase exposure and side effects.
- Strong CYP3A4 inducers may reduce effectiveness.
- Other medicines affecting nerves or blood counts may increase harm.
- Medicines that lower blood pressure may increase dizziness or fainting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.