About bortezomb
Proteasome inhibitor anticancer medicine
Used for
- Multiple myeloma
- Mantle cell lymphoma
Usual adult dose
Usually 1.3 mg/m² by injection, given on treatment schedules that vary by condition and combination.
Common side effects
- Peripheral nerve damage, tingling, or numbness
- Low blood counts
- Nausea, diarrhoea, or constipation
- Fatigue, fever, or shingles
Important warnings
- Can cause serious nerve, blood, heart, lung, or liver problems.
- Shingles may occur; preventive antiviral treatment is often considered.
- Avoid during pregnancy; effective contraception is required during treatment.
- Administer only under specialist supervision; dosing schedules and route matter.
Pregnancy
May harm an unborn baby. Avoid during pregnancy; effective contraception is required during treatment and for the period specified by the prescriber.
Breastfeeding
Breastfeeding is not recommended during treatment and for two months after the final dose.
Interactions
- Strong CYP3A4 inhibitors may increase exposure and side effects.
- Strong CYP3A4 inducers may reduce effectiveness.
- Medicines affecting blood pressure may increase low blood pressure risk.
- Other medicines causing nerve damage may worsen neuropathy.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.